Research Group Neuroplasticity

The main topics of our research group are cellular and molecular mechanisms of neuronal plasticity in the healthy brain, but also disorders of synaptic functions in neuropsychiatric and neurodegenerative diseases - so-called synaptopathies. We investigate the molecular dynamics of post-synapses, the decoding of neuronal calcium signals by calcium sensor proteins, the communication of synapses with the cell nucleus and how synaptic control of gene expression affects the plastic properties of synapses.

  • Head


    Michael Kreutz studied psychology, philosophy and linguistics at the University of Münster, Germany and then performed his PhD studies in Behavioral Neurosciences at the Ruhr University in Bochum, Germany. Subsequently he became a research fellow at the Department of Brain and Cognitive Sciences at MIT, USA. From 1990 to 1993 he was staff scientist in the Department of Molecular Neuroendocrinology at the Max Planck Institute for Experimental Medicine in Göttingen, Germany.

    In 1993 he moved to Magdeburg and he is currently head of the Neuroplasticity research group (NPlast) at the Leibniz Institute for Neurobiology.

    Since October 2015 he has a second affiliation at the Center for Molecular Neurobiology (ZMNH) in Hamburg where he is heading the Leibniz Group 'Dendritic Organelles and Synaptic Function'.


  • Members


    Dr. Michael
    Dr. Mohamed-Raafet
    Dr. Camilla
    Dr. Katarzyna Grochowska  
    Dr. Anna
    Dr. Ulrike
    Dr. Jeffrey Lopez
    Dr. Guilherme Monteiro Gomes
    Dr. Rajeev
    Dr. Irene Reyes Resina
    Dr. PingAn Yuan
    PhD students  
    Maximilian Borgmeyer  
    Michael Bucher  
    Vservolod Cherepashkin
    Eleónóra Cuboni
    Marie Oulé
    Marit Sperveslage  
    Judith Wolf
    Technical staff members  
    Dr. Maria Andres-Alonso  
    Dr. Julia Bär  
    Prof. Dr. Thomas Behnisch  
    Dr. Marina Mikhaylova  


  • Projects


    Research in NPlast is concerned with fundamental questions on how synapses communicate with the nucleus, how gene activity-dependent gene expression feeds back to synaptic function and how this is related to the formation of a cellular engram and last but not least how the nanoscale organization of the synapse determines functional properties in the context of learning and memory.

    We use a multi-disciplinary approach with studies ranging from single molecules to in vivo animal experimentation. We also address translational aspects where we try to understand whether the processes that we investigate might be relevant for disease.


    Project: ProCognito

    The ProCognito project aims to develop new approaches based on plant-derived active substances that help to maintain cognitive performance in old age. In the long term, these plant-based active compounds might help older people to lead healthy and self-determined lives, both preventively and therapeutically.

    ProCognito is part of the interdisciplinary research network "Autonomy in old age" and is realized in cooperation with the Leibniz Institute of Plant Biochemistry (IPB) Halle. Dr. Michael Kreutz is the project leader at the Leibniz Institute of Neurobiology (LIN).

    The research project focuses on the aging synapse as the nucleation point of the decline in cognitive performance. The molecular dynamics of synapses plays a crucial role not only in normal aging, but also in the early stages of the development of Alzheimer's dementia and other neurodegenerative diseases. Of particular relevance are findings showing that synaptic communication processes are disturbed in normal age by inflammatory diseases and factors involved in the metabolic syndrome.

    In addition, the Leibniz E-Center is to be expanded in order to introduce innovative approaches to e-research and to link the research infrastructure of the participating institutes. For this purpose, the data obtained will be entered into the digitized active compound database of the IPB. The data can thus also be used for future applications.


    More information are available here:

  • Current Third Party Funds

    Current Third Party Funds


    DFG SFB 779 TP B8

    DFG FOR 2419: Plasticity versus Stability - Molecular Mechanisms of Synaptic Strength

    DFG RTG 2413 'SynAge'

    DFG Kr1879 6-1

    BMBF ENERGI 01GQ1421

    LSA Exzellenzinitiave AiA Metabolisches Syndrom

    LSA Exzellenzinitiave AiA ProCognito

    Leibniz SAW Synaptoneurolipidomics

    Leibniz SAW Neurotranslation

    Leibniz SAW SyMetAge


  • Publications



    Neumann JR, Dash-Wagh S, Jack A, Räk A, Jüngling K, Hamad MIK, Pape H-C, Kreutz MR, Puskarjov M, Wahle P. 2019. The primate-specific peptide Y-P30 regulates morphological maturation of neocortical dendritic spines. PLoS ONE. 14(2).

    Mundhenk J, Fusi C, Kreutz MR. 2019. Caldendrin and Calneurons-EF-Hand CaM-Like Calcium Sensors With Unique Features and Specialized Neuronal Functions. Frontiers in Molecular Neuroscience. 12.

    Kiran U, Kreutz MR, Sharma Y, Chakraborty A. 2019. Tryptophan Scanning Mutagenesis of EF-Hand Motifs. Methods in molecular biology (Clifton, N.J.). 1929:567-581.



    Kaushik R, Morkovin E, Schneeberg J, Confettura AD, Kreutz MR, Senkov O, Dityatev A. 2018. Traditional Japanese Herbal Medicine Yokukansan Targets Distinct but Overlapping Mechanisms in Aged Mice and in the 5xFAD Mouse Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 10.

    Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T. 2018. JAK2-V617F promotes venous thrombosis through β12 integrin activation. Journal of Clinical Investigation. 128(10):4359-4371.

    Franco R, Aguinaga D, Reyes I, Canela EI, Lillo J, Tarutani A, Hasegawa M, del Ser-Badia A, del Rio JA, Kreutz MR, Saura CA, Navarro G. 2018. N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APPSw,Ind Mice. Frontiers in Molecular Neuroscience. 11:273.

    Mikhaylova M, Kreutz MR. 2018. Geclusterte Plastizität bei Langzeitpotenzierung: Wie starke Synapsen bestehen bleiben, um Langzeitgedächtnis aufrechtzuerhalten. Neuroforum. 24(3):195-201.,

    Angelats E, Requesens M, Aguinaga D, Kreutz MR, Franco R, Navarro G. 2018. Neuronal calcium and cAMP cross-talk mediated by cannabinoid CB1 receptor and EF-hand calcium sensor interactions. Frontiers in Cell and Developmental Biology. 6(JUL):67.

    Dumenieu M, Senkov O, Mironov A, Bourinet E, Kreutz MR, Dityatev A, Heine M, Bikbaev A, Lopez-Rojas J. 2018. The low-threshold calcium channel Cav3.2 mediates burst firing of mature dentate granule cells. Cerebral Cortex. 28(7):2594-2609.

    Heise C, Preuss JM, Schroeder JC, Battaglia CR, Kolibius J, Schmid R, Kreutz MR, Kas MJH, Burbach JPH, Boeckers TM. 2018. Heterogeneity of cell surface glutamate and GABA receptor expression in shank and CNTN4 autism mouse models. Frontiers in Molecular Neuroscience. 11.

    Bayraktar G, Kreutz MR. 2018. The Role of Activity-Dependent DNA Demethylation in the Adult Brain and in Neurological Disorders. Frontiers in Molecular Neuroscience. 11:169.

    Yun D, Zhuang Y, Kreutz MR, Behnisch T. 2018. The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. Neuropharmacology. 133:354-365.

    Bayraktar G, Kreutz MR. 2018. Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression?. Neuroscientist. 24(2):171-185.

    Mikhaylova M, Bär J, van Bommel B, Schätzle P, YuanXiang PA, Raman R, Hradsky J, Konietzny A, Loktionov EY, Reddy PP, Lopez-Rojas J, Spilker C, Kobler O, Raza SA, Stork O, Hoogenraad CC, Kreutz MR. 2018. Caldendrin Directly Couples Postsynaptic Calcium Signals to Actin Remodeling in Dendritic Spines. Neuron. 97(5):1110-1125.e14.



    Homiack D, O'Cinneide E, Hajmurad S, Barrileaux B, Stanley M, Kreutz MR, Schrader LA. 2017. Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus. Hippocampus. 27(9):1016-1029. Available from: 10.1002/hipo.22749

    Zhao B, Meka DP, Scharrenberg R, König T, Schwanke B, Kobler O, Windhorst S, Kreutz MR, Mikhaylova M, Calderon De Anda F. 2017. Microtubules Modulate F-actin Dynamics during Neuronal Polarization. Scientific Reports. 7(1). Available from: 10.1038/s41598-017-09832-8

    Kiran U, Regur P, Kreutz MR, Sharma Y, Chakraborty A. 2017. Intermotif Communication Induces Hierarchical Ca2+ Filling of Caldendrin. Biochemistry. 56(19):2467-2476. Available from: 10.1021/acs.biochem.7b00132

    Duménieu M, Oulé M, Kreutz MR, Lopez-Rojas J. 2017. The segregated expression of voltage-gated potassium and sodium channels in neuronal membranes: Functional implications and regulatory mechanisms. Frontiers in Cellular Neuroscience. 11. Available from: 10.3389/fncel.2017.00115

    Katrukha EA, Mikhaylova M, van Brakel HX, Van Bergen En Henegouwen PMP, Akhmanova A, Hoogenraad CC, Kapitein LC. 2017. Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots. Nature Communications. 8. Available from: 10.1038/ncomms14772

    Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR. 2017. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO Reports. 18(6):962-981. Available from: 10.15252/embr.201643519



    Spilker C, Grochowska KM, Kreutz MR. 2016. What do we learn from the murine Jacob/Nsmf gene knockout for human disease?. Rare Diseases. 4(1):e1241361. Available from: 10.1080/21675511.2016.1241361

    Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schlüter D, Reinhold D, Jordan BA, Gintschel P, Schraven B, Kreutz MR. 2016. Normal development and function of T cells in proline rich 7 (Prr7) deficient mice. PLoS ONE. 11(9). Available from: 10.1371/journal.pone.0162863

    Kravchick DO, Karpova A, Hrdinka M, Lopez-Rojas J, Iacobas S, Carbonell AU, Iacobas DA, Kreutz MR, Jordan BA. 2016. Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity. EMBO Journal. 35(17):1923-1934. Available from: 10.15252/embj.201593070

    Melgarejo da Rosa M, Yuanxiang PA, Brambilla R, Kreutz MR, Karpova A. 2016. Synaptic GluN2B/CaMKII-α signaling induces synapto-nuclear transport of ERK and jacob. Frontiers in Molecular Neuroscience. 9(AUG). Available from: 10.3389/fnmol.2016.00066

    Bera S, Raghuram V, Mikhaylova M, Kreutz MR. 2016. A plasmid-based expression system to study protein-protein interactions at the Golgi in vivo. Analytical Biochemistry. 502:50-52. Available from: 10.1016/j.ab.2016.02.016

    Lopez-Rojas J, Kreutz MR. 2016. Mature granule cells of the dentate gyrus-Passive bystanders or principal performers in hippocampal function?. Neuroscience and Biobehavioral Reviews. 64:167-174. Available from: 10.1016/j.neubiorev.2016.02.021

    Heise C, Schroeder JC, Schoen M, Halbedl S, Reim D, Woelfle S, Kreutz MR, Schmeisser MJ, Boeckers TM. 2016. Selective localization of shanks to VGLUT1-positive excitatory synapses in the mouse hippocampus. Frontiers in Cellular Neuroscience. 10(APR). Available from: 10.3389/fncel.2016.00106

    Kevenaar JT, Bianchi S, Van Spronsen M, Olieric N, Lipka J, Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, De Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC. 2016. Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity. Current Biology. 26(7):849-861. Available from: 10.1016/j.cub.2016.01.048

    Yuan Xiang P, Janc O, Grochowska KM, Kreutz MR, Reymann KG. 2016. Dopamine agonists rescue Aβ-induced LTP impairment by Src-family tyrosine kinases. Neurobiology of Aging. 40:98-102. Available from: 10.1016/j.neurobiolaging.2016.01.008

    Dinamarca MC, Guzzetti F, Karpova A, Lim D, Mitro N, Musardo S, Mellone M, Marcello E, Stanic J, Samaddar T, Burguière A, Caldarelli A, Genazzani AA, Perroy J, Fagni L, Canonico PL, Kreutz MR, Gardoni F, Di Luca M. 2016. Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus. eLife. 5(MARCH2016). Available from: 10.7554/eLife.12430.001

    Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, YuanXiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bär J, D’Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR. 2016. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genetics. 12(3). Available from: 10.1371/journal.pgen.1005907

    Lopez-Rojas J, Heine M, Kreutz MR. 2016. Plasticity of intrinsic excitability in mature granule cells of the dentate gyrus. Scientific Reports. 6. Available from: 10.1038/srep21615

    Dieterich DC, Kreutz MR. 2016. Proteomics of the synapse - A quantitative approach to neuronal plasticity. Molecular and Cellular Proteomics. 15(2):368-381. Available from: 10.1074/mcp.R115.051482

    Mikhaylova M, Bera S, Kobler O, Frischknecht R, Kreutz MR. 2016. A Dendritic Golgi Satellite between ERGIC and Retromer. Cell Reports. 14(2):189-199. Available from: 10.1016/j.celrep.2015.12.024

    Bera S, Bayraktar G, Grochowska KM, da Rosa MM, Kreutz MR. 2016. Activity dependent protein transport from the synapse to the nucleus. In Dendrites: Development and Disease. Springer Japan. pp. 111-124. Available from: 10.1007/978-4-431-56050-0_5

    Bikbaev A, Duménieu M, Lopez-Rojas J, Heine M. 2016. Localising receptors and channels across the dendritic arbour. In Dendrites: Development and Disease. Springer Japan. pp. 387-424. Available from: 10.1007/978-4-431-56050-0_16



    Hradsky J, Bernstein HG, Marunde M, Mikhaylova M, Kreutz MR. 2015. Alternative Splicing, Expression and Cellular Localization of Calneuron-1 in the Rat and Human Brain. Journal of Histochemistry and Cytochemistry. 63(10):793-804. Available from: 10.1369/0022155415595841

    Mikhaylova M, Cloin BMC, Finan K, Van Den Berg R, Teeuw J, Kijanka MM, Sokolowski M, Katrukha EA, Maidorn M, Opazo F, Moutel S, Vantard M, Perez F, Van Bergen En Henegouwen PMP, Hoogenraad CC, Ewers H, Kapitein LC. 2015. Resolving bundled microtubules using anti-tubulin nanobodies. Nature Communications. 6. Available from: 10.1038/ncomms8933

    Neumann JR, Dash-Wagh S, Jüngling K, Tsai T, Meschkat M, Räk A, Schönfelder S, Riedel C, Hamad MIK, Wiese S, Pape H-C, Gottmann K, Kreutz MR, Wahle P. 2015. Y-P30 promotes axonal growth by stabilizing growth cones. Brain Structure and Function. 220(4):1935-1950. Available from: 10.1007/s00429-014-0764-2

    Lever MB, Karpova A, Kreutz MR. 2015. An importin code in neuronal transport from synapse-to-nucleus?. Frontiers in Molecular Neuroscience. 8(JULY). Available from: 10.3389/fnmol.2015.00033

    Panayotis N, Karpova A, Kreutz MR, Fainzilber M. 2015. Macromolecular transport in synapse to nucleus communication. Trends in Neurosciences. 38(2):108-116. Available from: 10.1016/j.tins.2014.12.001

    Bera S, Thillai K, Sriraman K, Jayaraman G. 2015. Process strategies for enhancing recombinant streptokinase production in Lactococcus lactis cultures using P170 expression system. Biochemical Engineering Journal. 93:94-101. Available from: 10.1016/j.bej.2014.07.009



    Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ, Ferré S. 2014. Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers. Chemistry and Biology. 21(11):1546-1566. Available from: 10.1016/j.chembiol.2014.10.004

    Rosenberg T, Gal-Ben-Ari S, Dieterich DC, Kreutz MR, Ziv NE, Gundelfinger ED, Rosenblum K. 2014. The roles of protein expression in synaptic plasticity and memory consolidation. Frontiers in Molecular Neuroscience. 7(November). Available from: 10.3389/fnmol.2014.00086

    Kaushik R, Grochowska KM, Butnaru I, Kreutz MR. 2014. Protein trafficking from synapse to nucleus in control of activity-dependent gene expression. Neuroscience. 280:340-350. Available from: 10.1016/j.neuroscience.2014.09.011

    Yuanxiang P, Bera S, Karpova A, Kreutz MR, Mikhaylova M. 2014. Isolation of CA1 nuclear enriched fractions from hippocampal slices to study activity-dependent nuclear import of synapto-nuclear messenger proteins. Journal of Visualized Experiments. (90). Available from: 10.3791/51310

    Reddy PP, Raghuram V, Hradsky J, Spilker C, Chakraborty A, Sharma Y, Mikhaylova M, Kreutz MR. 2014. Molecular dynamics of the neuronal EF-hand Ca2+-sensor Caldendrin. PLoS ONE. 9(7). Available from: 10.1371/journal.pone.0103186

    Mikhaylova M, Schumacher A, Borutzki C, Neumann JR, Macharadze T, El-Mousleh T, Wahle P, Zenclussen AC, Kreutz MR. 2014. Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. BMC Research Notes. 7(1). Available from: 10.1186/1756-0500-7-400

    Gomes GM, Dalmolin GD, Bär J, Karpova A, Mello CF, Kreutz MR, Rubin MA. 2014. Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: Involvement of extrasynaptic NMDA receptors. PLoS ONE. 9(6). Available from: 10.1371/journal.pone.0099184

    Sahu G, Sukumaran S, Bera AK. 2014. Pannexins form gap junctions with electrophysiological and pharmacological properties distinct from connexins. Scientific Reports. 4. Available from: 10.1038/srep04955

    Fan W, Fu T. 2014. Somatostatin modulates LTP in hippocampal CA1 pyramidal neurons: Differential activation conditions in apical and basal dendrites. Neuroscience Letters. 561:1-6. Available from: 10.1016/j.neulet.2013.12.025

    Landgraf P, Mikhaylova M, Macharadze T, Borutzki C, Zenclussen AC, Wahle P, Kreutz MR. 2014. Binding of Y-P30 to syndecan 2/3 regulates the nuclear localization of CASK. PLoS ONE. 9(2). Available from: 10.1371/journal.pone.0085924

    Mikhaylova M, Karpova A, Bär J, Bethge P, YuanXiang P, Chen Y, Zuschratter W, Behnisch T, Kreutz MR. 2014. Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain. Brain Structure and Function. 219(3):843-860. Available from: 10.1007/s00429-013-0539-1

    Bera S, Kreutz MR. 2014. When synaptic proteins meet the genome: Transcriptional regulation in cell death and plasticity by the synapto-nuclear messenger jacob. Neuropsychopharmacology. 39(1):245-246. Available from: 10.1038/npp.2013.204

    Grabrucker S, Jannetti L, Eckert M, Gaub S, Chhabra R, Pfaender S, Mangus K, Reddy PP, Rankovic V, Schmeisser MJ, Kreutz MR, Ehret G, Boeckers TM, Grabrucker AM. 2014. Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders. Brain. 137(1):137-152. Available from: 10.1093/brain/awt303



    Fan W. 2013. Group I metabotropic glutamate receptors modulate late phase long-term potentiation in hippocampal CA1 pyramidal neurons: Comparison of apical and basal dendrites. Neuroscience Letters. 553:132-137. Available from: 10.1016/j.neulet.2013.08.030

    Heine M, Karpova A, Gundelfinger ED. 2013. Counting gephyrins, one at a time: A nanoscale view on the inhibitory postsynapse. Neuron. 79(2):213-216. Available from: 10.1016/j.neuron.2013.07.004

    Karpova A, Mikhaylova M, Bera S, Bär J, Reddy PP, Behnisch T, Rankovic V, Spilker C, Bethge P, Sahin J, Kaushik R, Zuschratter W, Kähne T, Naumann M, Gundelfinger ED, Kreutz MR. 2013. Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus. Cell. 152(5):1119-1133. Available from: 10.1016/j.cell.2013.02.002

    van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC. 2013. TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites. Neuron. 77(3):485-502. Available from: 10.1016/j.neuron.2012.11.027

    Hradsky J, Mikhaylova M, Karpova A, Kreutz MR, Zuschratter W. 2013. Super-resolution microscopy of the neuronal calcium-binding proteins calneuron-1 and caldendrin. In Methods in Molecular Biology. pp. 147-169. (Methods in Molecular Biology). Available from: 10.1007/978-1-62703-230-8_10



    Bernstein HG, Smalla KH, Dürrschmidt D, Keilhoff G, Dobrowolny H, Steiner J, Schmitt A, Kreutz MR, Bogerts B. 2012. Increased density of prohibitin-immunoreactive oligodendrocytes in the dorsolateral prefrontal white matter of subjects with schizophrenia suggests extraneuronal roles for the protein in the disease. NeuroMolecular Medicine. 14(4):270-280. Available from: 10.1007/s12017-012-8185-y

    Seeger C, Gorny X, Reddy PP, Seidenbecher C, Danielson UH. 2012. Kinetic and mechanistic differences in the interactions between caldendrin and calmodulin with AKAP79 suggest different roles in synaptic function. Journal of Molecular Recognition. 25(10):495-503. Available from: 10.1002/jmr.2215

    Kreutz MR, Naranjo JR, Koch KW, Schwaller B. 2012. The neuronal functions of EF-hand Ca 2+-binding proteins. Frontiers in Molecular Neuroscience. (SEPTEMBER):1.

    Ehling P, Kanyshkova T, Baumann A, Landgraf P, Meuth SG, Pape HC, Budde T. 2012. Adenylyl cyclases: Expression in the developing rat thalamus and their role in absence epilepsy. Journal of Molecular Neuroscience. 48(1):45-52. Available from: 10.1007/s12031-012-9767-8

    Kreutz MR, Koch KW, Naranjo JR, Schwaller B. 2012. Editorial for the Research topic 'The neuronal functions of EF-hand Ca2+-binding proteins' in Frontiers in Molecular Neuroscience. Frontiers in Molecular Neuroscience. (AUG 2012):1-2. Available from: 10.3389/fnmol.2012.00092

    Gorny X, Mikhaylova M, Seeger C, Reddy PP, Reissner C, Schott BH, Helena Danielson U, Kreutz MR, Seidenbecher C. 2012. AKAP79/150 interacts with the neuronal calcium-binding protein caldendrin. Journal of Neurochemistry. 122(4):714-726. Available from: 10.1111/j.1471-4159.2012.07828.x

    MacHaradze T, Pielot R, Wanger T, Scheich H, Gundelfinger ED, Budinger E, Goldschmidt J, Kreutz MR. 2012. Altered neuronal activity patterns in the visual cortex of the adult rat after partial optic nerve crush-a single-cell resolution metabolic mapping study. Cerebral Cortex. 22(8):1824-1833. Available from: 10.1093/cercor/bhr256

    Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck ST, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmitz D, Kreutz MR, Bourgeron T, Gundelfinger ED, Boeckers TM. 2012. Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature. 486(7402):256-260. Available from: 10.1038/nature11015

    Raghuram V, Sharma Y, Kreutz MR. 2012. Ca 2+ sensor proteins in dendritic spines: A race for Ca 2+. Frontiers in Molecular Neuroscience. (MAY 2012). Available from: 10.3389/fnmol.2012.00061

    Navarro G, Hradsky J, Lluís C, Casadó V, McCormick PJ, Kreutz MR, Mikhaylova M. 2012. NCS-1 associates with adenosine A 2A receptors and modulates receptor function. Frontiers in Molecular Neuroscience. (APRIL). Available from: 10.3389/fnmol.2012.00053

    Chen Y, Yuanxiang P, Knöpfel T, Thomas U, Behnisch T. 2012. Hippocampal LTP triggers proteasome-mediated SPAR degradation in CA1 neurons. Synapse. 66(2):142-150. Available from: 10.1002/syn.20994

    Karpova A, Bär J, Kreutz MR. 2012. Long-distance signaling from synapse to nucleus via protein messengers. In Advances in Experimental Medicine and Biology. Springer. pp. 355-376. (Advances in Experimental Medicine and Biology). Available from: 10.1007/978-3-7091-0932-8_16

    Kreutz MR, Sala C. 2012. Postsynaptic molecular mechanisms. Preface. Advances in Experimental Medicine and Biology. 970.

    Kreutz MR, Sala C, ed. 2012. Synaptic Plasticity: Dynamics, Development and Disease. Wien: Springer. 622 p. (Advances in Experimental Medicine and Biology). Available from: 10.1007/978-3-7091-0932-8



    Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth SG, Kreutz MR, Budde T, Munsch T. 2011. Modulation of calcium-dependent inactivation of L-type Ca 2+ channels via β-adrenergic signaling in thalamocortical relay neurons. PLoS ONE. 6(12). Available from: 10.1371/journal.pone.0027474

    Rönicke R, Mikhaylova M, Rönicke S, Meinhardt J, Schröder UH, Fändrich M, Reiser G, Kreutz MR, Reymann KG. 2011. Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiology of Aging. 32(12):2219-2228. Available from: 10.1016/j.neurobiolaging.2010.01.011

    Fainzilber M, Budnik V, Segal RA, Kreutz MR. 2011. From synapse to nucleus and back again-communication over distance within neurons. Journal of Neuroscience. 31(45):16045-16048. Available from: 10.1523/JNEUROSCI.4006-11.2011

    Dash-Wagh S, Neumann JR, Veitinger S, Grote-Westrick C, Landgraf P, Pape HC, Kreutz MR, von Holst A, Wahle P. 2011. The survival promoting peptide Y-P30 promotes cellular migration. Molecular and Cellular Neurosciences. 48(3):195-204. Available from: 10.1016/j.mcn.2011.07.005

    Hradsky J, Raghuram V, Pasham P, Navarro G, Hupe M, Casado V, McCormick PJ, Sharma Y, Kreutz MR, Mikhaylova M. 2011. Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca 2+ sensor calneurons requires the TRC40/Asna1 protein chaperone. Journal of Biological Chemistry. 286(42):36762-36776. Available from: 10.1074/jbc.M111.280339

    Mikhaylova M, Hradsky J, Kreutz MR. 2011. Between promiscuity and specificity: Novel roles of EF-hand calcium sensors in neuronal Ca 2+ signalling. Journal of Neurochemistry. 118(5):695-713. Available from: 10.1111/j.1471-4159.2011.07372.x

    MacHaradze T, Landgraf P, Pape HC, Wahle P, Kreutz MR. 2011. Y-P30 confers neuroprotection after optic nerve crush in adult rats. NeuroReport. 22(11):544-547. Available from: 10.1097/WNR.0b013e328348b512

    Engmann O, Hortobágyi T, Pidsley R, Troakes C, Bernstein HG, Kreutz MR, Mill J, Nikolic M, Giese KP. 2011. Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition. Brain. 134(8):2408-2421. Available from: 10.1093/brain/awr155

    Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U. 2011. Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth. Biochimica et Biophysica Acta - Molecular Cell Research. 1813(5):1025-1037. Available from: 10.1016/j.bbamcr.2010.12.023

    Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, Boeckers TM. 2011. Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO Journal. 30(3):569-581. Available from: 10.1038/emboj.2010.336

    Behnisch T, YuanXiang P, Bethge P, Parvez S, Chen Y, Yu J, Karpova A, Frey JU, Mikhaylova M, Kreutz MR. 2011. Nuclear translocation of Jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression. PLoS ONE. 6(2). Available from: 10.1371/journal.pone.0017276



    Spilker C, Kreutz MR. 2010. RapGAPs in brain: Multipurpose players in neuronal Rap signalling. European Journal of Neuroscience. 32(1):1-9. Available from: 10.1111/j.1460-9568.2010.07273.x

    Fries R, Reddy PP, Mikhaylova M, Haverkamp S, Wei T, Müller M, Kreutz MR, Koch KW. 2010. Dynamic cellular translocation of caldendrin is facilitated by the Ca 2+-myristoyl switch of recoverin. Journal of Neurochemistry. 113(5):1150-1162. Available from: 10.1111/j.1471-4159.2010.06676.x

    Dürrschmidt D, Smalla KH, Kreutz MR, Dobrowolny H, Steiner J, Keilhoff G, Bogerts B, Bernstein HG. 2010. Increased oligodendroglial expression of the cell proliferation?controlling protein prohibitin in schizophrenia. A hint for cell cycle abnormalities?. Acta Clinica Croatica. 49(SUPPL. 2):39-41.

    Rankovic V, Ehling P, Coulon P, Landgraf P, Kreutz MR, Munsch T, Budde T. 2010. Intracellular Ca2+ release-dependent inactivation of Ca 2+ currents in thalamocortical relay neurons. European Journal of Neuroscience. 31(3):439-449. Available from: 10.1111/j.1460-9568.2010.07081.x

    Mikhaylova M, Reddy PP, Kreutz MR. 2010. Role of neuronal Ca2+-sensor proteins in Golgi-cell-surface membrane traffic. Biochemical Society Transactions. 38(1):177-180. Available from: 10.1042/BST0380177

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