Department Systems Physiology of Learning
In the Department "Systems Physiology of Learning", we investigate neuronal mechanisms of diverse phenomena in the context of learning and memory. We focus predominantly on the level of neuronal circuits, both within selected brain regions and as connections between brain regions. To investigate the neuronal mechanisms underlying learning we combine behavioral experiments, including detection, discrimination and categorization learning, with electrophysiological recording (of single cells, cell assemblies, local field potentials, electrocorticograms and EEG), with optical recording (using voltage-sensitive dyes and Ca2+ imaging), and with optogenetic, electrical and pharmacological intervention strategies.
Within the last years, we have successfully finalized our projects in the Collaborative Research Centers CRC TRR 31 (Active listening) and CRC TRR 62 (A companion technology for techncial communication systems)and CRC 779 (Neurobiology of motivated behavior), as well as our project in the USA-German Collaboration on Computational Neuroscience.
- Head
Head
Frank Ohl studied biology at the technical University of Darmstadt where he received his diploma, on the topic of learning-induced cortical receptive field plasticity, and his doctorate on nonlinear interactions between spectral components in cortical representation of complex sounds, both with distinction. He spent his postdoctoral phase with Walter J. Freeman at UC Berkeley, USA, on mechanisms underlying cortical neurodynamics during perception and learning. He is fascinated how in modern neuroscience, novel cutting-edge technologies meet age-old questions about the nature of the mind, and advocates that modern brain research should transcend traditional disciplines in science. His teaching and lecture activities focus on systems neuroscience but also include many interdisciplinary topics, ranging from classical electrodynamics to philosophical implications of neuroscience for law. His department assembles a group of highly motivated scientists with a converging interest in circuit-level neurophysiology.
Frank Ohl has been the spokesman of the recently successfully completed Magdeburg CRC 779 (Neurobiology of motivated behavior), as well as the local spokesman of the transregional (Oldenburg-Magdeburg) CRC TRR 31 (Active Listening) and coordinator of the Leibniz Postdoctoral Network (LPN, Impact of monoamines on neuronal circuits).
- Members
Members
Head Prof. Dr. Frank Ohl +49-391-6263-95481 frank.ohl@lin-magdeburg.de Sekretaries Beate Traoré +49-391-6263-95481 beate.traore@lin-magdeburg.de Postdocs PD Dr. Max Happel +49-391-6263-94411 max.happel@lin-magdeburg.de Dr. Michael Lippert +49-391-6263-94391 michael.lippert@lin-magdeburg.de Dr. Andreas Schulz +49-391-6263-94381 andreas.schulz@lin-magdeburg.de PhD students Tamer Ayberk Kaya +49-391-6263-94401 TamerAyberk.Kaya@lin-magdeburg.de Tony de Schultz +49-391-6263-94401 tony.schultz@lin-magdeburg.de Alisa Vlasenko +49-391-6263-93481 alisa.vlasenko@lin-magdeburg.de Zifeng Xia +49-391-6263-93481 zifeng.xia@lin-magdeburg.de Technical staff members Anja Gürke +49-391-6263-95461 anja.guerke@lin-magdeburg.de Ute Lerke +49-391-6263-95081 ute.lerke@lin-magdeburg.de Kathrin Ohl +49-391-6263-95461 kathrin.ohl@lin-magdeburg.de Guests PD Dr. Maike Vollmer +49-391-6263-95491 Dr. Dr. Kentaroh Takagaki Dr. Tamar Macharadze - Projects
Projects
The CRC 779 (Neurobiology of motivated behavior), whose coordinator is the director of this department, has started the third funding period after successful evaluation. Here we investigate the interaction of sensory brain regions with those regions that generate "meaning" in the brain.
Our project in the DFG Priority Program 1665 (Resolving and manipulating neuronal networks in the mammalian brain) has entered into its renewed funding phase. Here we want to go beyond the correlative research strategies established in the neurosciences and investigate causal mechanisms, i.e. support learning performance in the individual by specific manipulation of brain processes.
In the framework of the EU-funded International Graduate School ABINEP (Analysis, imaging, and modelling of neuronal and inflammatory processes) we investigate the influence of the neurotransmitter dopamine on the communication between sensory and meaning-evaluating brain structures.
The neuronal mechanisms that underlie the phenomenon of behavioral strategy change are investigated in the new project IAIS (Intention-based anticipatory interactive systems) in collaboration with colleagues from the Faculty of Electrical Engineering and Information Technology and the Faculty of Computer Science from OVGU.
- Third-party funding
Third-party funding
2008-2019
DFG SFB 779 Neurobiologie motiverten Verhaltens
Sprecher und TP B1 Interaktion sensorischer und Verstärker-evaluierender Systeme beim auditorischen Lernen
http://www.sfb779.de/b01.html
http://gepris.dfg.de/gepris/projekt/638946032008-2019
DFG SFB 779 Neurobiologie motiverten Verhaltens
Integriertes Graduiertenkolleg (zusammen mit Bertram Gerber)
http://www.sfb779.de
http://gepris.dfg.de/gepris/projekt/2163428792008-2019
DFG SFB 779 Neurobiologie motiverten Verhaltens
Z2 Zentralprojekt
http://www.sfb779.de
http://gepris.dfg.de/gepris/projekt/639356942017-2021
ABINEP: Analysis, imaging, and modelling of neuronal and inflammatory processes
Dopamine-dependent modulation of neuronal switches in the auditory cortex and the striatum
https://www.abinep.ovgu.de/2016-2019
DFG SPP 1665 Resolving and manipulating neuronal networks in the mammalian brain
TP Causative mechanisms of mesoscopic activity patterns in auditory category discrimination (zusammen mit Bertram Schmidt und Sonja Grün)
http://www.spp1665.de/projects_causative.html2018-2020
Intentional anticipatory interactive systems (IAIS)
Neurobiologie des Strategiewechsels. Unterstützung und Intervention2015-2018
WGL The Leibniz Postdoctoral Network (LPN) at the LIN
Monoaminergic impact on neuronal circuits
http://lpn.lin-magdeburg.de/2013-2019
DFG SPP 1608 "Ultrafast and temporally precise information processing: Normal and dysfunctional hearing"
"Age-dependent effects of unilateral hearing loss on the processing of interaural time differences and possible readjustments by subsequent electric cochlear stimulation" (Vollmer)
http://www.pp1608.com/the-group/maike-vollmer.html"Mechanisms of the phase–locking of auditory-nerve fibers: a modeling approach" (Heil)
http://www.pp1608.com/the-group/peter-heil.html2013-2019
DFG SPP 1665
"Causative Mechanisms of Mesoscopic Activity Patterns in Auditory Category Discrimination" (Ohl/Takagaki)
http://www.spp1665.de/projects_causative.html - Publications
Publications
Key publications
Peterson AJ, Heil P. 2020. Phase locking of auditory-nerve fibers: the role of lowpass filtering by hair cells. Journal of Neuroscience. 40(24):4700-4714. https://doi.org/10.1523/JNEUROSCI.2269-19.2020
Deane KE, Brunk MGK, Curran AW, Zempeltzi MM, Ma J, Lin X, Abela F, Aksit S, Deliano M, Ohl FW, Happel MFK. 2020. Ketamine anaesthesia induces gain enhancement via recurrent excitation in granular input layers of the auditory cortex. Journal of Physiology. 598(13):2741-2755. https://doi.org/10.1113/JP279705
Deliano M, Brunk MGK, El-Tabbal M, Zempeltzi MM, Happel MFK, Ohl FW. 2020. Dopaminergic neuromodulation of high gamma stimulus phase-locking in gerbil primary auditory cortex mediated by D1/D5-receptors. European Journal of Neuroscience. 51(5):1315-1327. https://doi.org/10.1111/ejn.13898
Weidner TC, Vincenz D, Brocka M, Tegtmeier J, Oelschlegel AM, Ohl FW, Goldschmidt J, Lippert MT. 2020. Matching stimulation paradigms resolve apparent differences between optogenetic and electrical VTA stimulation. Brain Stimulation. 13(2):363-371. https://doi.org/10.1016/j.brs.2019.11.005
Brunk MGK, Deane KE, Kisse M, Deliano M, Vieweg S, Ohl FW, Lippert MT, Happel MFK. 2019. Optogenetic stimulation of the VTA modulates a frequency-specific gain of thalamocortical inputs in infragranular layers of the auditory cortex. Scientific Reports. 9(1):Article 20385. https://doi.org/10.1038/s41598-019-56926-6
Niekisch H, Steinhardt J, Berghäuser J, Bertazzoni S, Kaschinski E, Kasper J, Kisse M, Mitlöhner J, Singh JB, Weber J, Frischknecht R, Happel MFK. 2019. Learning induces transient upregulation of brevican in the auditory cortex during consolidation of long-term memories. Journal of Neuroscience. 39(36):7049-7060. https://doi.org/10.1523/JNEUROSCI.2499-18.2019
Brocka M, Helbing C, Vincenz D, Scherf T, Montag D, Goldschmidt J, Angenstein F*, Lippert M*. 2018. Contributions of dopaminergic and non-dopaminergic neurons to VTA-stimulation induced neurovascular responses in brain reward circuits. NeuroImage. 177:88-97. https://doi.org/10.1016/j.neuroimage.2018.04.059 *shared corresponding authorship
Heil P, Matysiak A, Neubauer H. 2017. A probabilistic Poisson-based model accounts for an extensive set of absolute auditory threshold measurements. Hearing Research. 353:135-161. https://doi.org/10.1016/j.heares.2017.06.011
Ohl FW. 2015. Role of cortical neurodynamics for understanding the neural basis of motivated behavior - lessons from auditory category learning. Current Opinion in Neurobiology. 31:88-94. doi.org/10.1016/j.conb.2014.08.014
Happel MFK, Niekisch H, Castiblanco Rivera LL, Ohl FW, Deliano M, Frischknecht R. 2014. Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex. Proceedings of the National Academy of Sciences of the United States of America. 111(7):2800-2805. https://doi.org/10.1073/pnas.1310272111
All publications of the department
2023
Danyeli LV, Sen ZD, Colic L, Kurzweil L, Gensberger-Reigl S, Macharadze T, Götting F, Refisch A, Liebe T, Chand T, Kretzschmar M, Wagner G, Opel N, Jollant F, Speck O, Munk M HJ, Li M, Walter M. 2023. Association of the delayed changes in glutamate levels and functional connectivity with the immediate network effects of S-ketamine. Translational Psychiatry. 13(1):Article 60. https://doi.org/10.1038/s41398-023-02346-0
Grochowska KM, Gomes GM, Raman R, Kaushik R, Sosulina L, Kaneko H, Oelschlegel AM, Yuanxiang P, Reyes-Resina I, Bayraktar G, Samer S, Spilker C, Woo MS, Morawski,M, Goldschmidt J, Friese MA, Rossner S, Navarro G, Remy S, Reissner C, Karpova A, Kreutz MR. 2023. Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease. The EMBO journal. 42(4):Article e112453. https://doi.org/10.15252/embj.2022112453
Klingner CM, Denker M, Grün S, Hanke M, Oeltze-Jafra S, Ohl FW, Radny J, Rotter S, Scherberger H, Stein A, Wachtler T, Witte OW, Ritter P. 2023. Research Data Management and Data Sharing for Reproducible Research - Results of a Community Survey of the German National Research Data Infrastructure Initiative Neuroscience. eNeuro. 10(2):Article ENEURO.0215-22.2023. https://doi.org/10.1523/ENEURO.0215-22.2023
2022
Caras ML, Happel MFK, Chandrasekaran B, Ripollés P, Keesom SM, Hurley LM, Remage-Healey L, Holt LL, Wright BA. 2022. Non-sensory Influences on Auditory Learning and Plasticity. JARO - Journal of the Association for Research in Otolaryngology. 23(2):151-166. https://doi.org/10.1007/s10162-022-00837-3
Happel MFK, Hechavarria JC, de Hoz L. 2022. Editorial: Cortical-Subcortical Loops in Sensory Processing. Frontiers in neural circuits. 16:Article 851612. https://doi.org/10.3389/fncir.2022.851612
Jeschke M, Ohl FW, Wang X. 2022. Effects of Cortical Cooling on Sound Processing in Auditory Cortex and Thalamus of Awake Marmosets. Frontiers in neural circuits. 15:Article 786740. https://doi.org/10.3389/fncir.2021.786740
Kowark A, Berger M, Rossaint R, Schmid M, Coburn M, Matcharadze T, POSE-Study group. 2022. Association between benzodiazepine premedication and 30-day mortality rate: A propensity-score weighted analysis of the Peri-interventional Outcome Study in the Elderly (POSE). European journal of anaesthesiology. 39(3):210-218. https://doi.org/10.1097/EJA.0000000000001638
Saldeitis K, Jeschke M, Michalek A, Henschke JU, Wetzel W, Ohl FW, Budinger E. 2022. Selective interruption of auditory interhemispheric crosstalk impairs discrimination learning of frequency-modulated tone direction but not gap detection and discrimination. Journal of Neuroscience. 42(10):2025-2038. https://doi.org/10.1523/JNEUROSCI.0216-21.2022
2021
Atucha E, Ku S-P, Lippert M, Sauvage M. 2021. Remembering the gist of an event over a lifetime depends on the hippocampus. bioRxiv. https://doi.org/10.1101/2021.04.14.439803
Brosch M, Vlasenko A, Ohl FW, Lippert MT. 2021. TetrODrive: an open-source microdrive for combined electrophysiology and optophysiology. Journal of Neural Engineering. 18(4):Article 046030. https://doi.org/10.1088/1741-2552/abf608
El-Tabbal M, Niekisch H, Henschke JU, Budinger E, Frischknecht R, Deliano M, Happel MFK. 2021. The extracellular matrix regulates cortical layer dynamics and cross-columnar frequency integration in the auditory cortex. Communications biology. 4(1):Article 322. https://doi.org/10.1038/s42003-021-01837-4
Heil P, Mohamed ESI, Matysiak A. 2021. Towards a unifying basis of auditory thresholds: Thresholds for multicomponent stimuli. Hearing Research. 410:Article 108349. https://doi.org/10.1016/j.heares.2021.108349
Heil P. 2021. Comparing and modeling absolute auditory thresholds in an alternative-forced-choice and a yes-no procedure. Hearing Research. 403:Article 108164. https://doi.org/10.1016/j.heares.2020.108164
Jeschke M, Happel MFK, Tziridis K, Krauss P, Schilling A, Schulze H, Ohl FW. 2021. Acute and Long-Term Circuit-Level Effects in the Auditory Cortex After Sound Trauma. Frontiers in Neuroscience. 14:Article 598406. https://doi.org/10.3389/fnins.2020.598406
Kozma R, Hu S, Sokolov Y, Wanger T, Schulz AL, Woldeit ML, Gonçalves AI, Ruszinkó M, Ohl FW. 2021. State Transitions During Discrimination Learning in the Gerbil Auditory Cortex Analyzed by Network Causality Metrics. Frontiers in Systems Neuroscience. 15:Article 641684. https://doi.org/10.3389/fnsys.2021.641684
Kreutzmann JC, Fendt M. 2021. Intranasal oxytocin compensates for estrus cycle-specific reduction of conditioned safety memory in rats: Implications for psychiatric disorders. Neurobiology of stress. 14:Article 100313. https://doi.org/10.1016/j.ynstr.2021.100313
Kreutzmann JC, Marin MF, Fendt M, Milad MR, Ressler K, Jovanovic T. 2021. Unconditioned response to an aversive stimulus as predictor of response to conditioned fear and safety: A cross-species study. Behavioural Brain Research. 402:Article 113105. https://doi.org/10.1016/j.bbr.2020.113105
Lin X, Brunk MGK, Yuanxiang P, Curran AW, Zhang E, Stöber F, Goldschmidt J, Gundelfinger ED, Vollmer M, Happel MFK, Herrera-Molina R, Montag D. 2021. Neuroplastin expression is essential for hearing and hair cell PMCA expression. Brain Structure and Function. 226(5):1533-1551. https://doi.org/10.1007/s00429-021-02269-w
Peterson AJ, Heil P. 2021. A simplified physiological model of rate-level functions of auditory-nerve fibers. Hearing Research. 406:Article 108258. https://doi.org/10.1016/j.heares.2021.108258
Peterson AJ. 2021. A numerical method for computing interval distributions for an inhomogeneous Poisson point process modified by random dead times. Biological Cybernetics. 115(2):177-190. https://doi.org/10.1007/s00422-021-00868-8
Prior MJW, Bast T, McGarrity S, Goldschmidt J, Vincenz D, Seaton A, Hall G, Pitiot A. 2021. Ratlas-LH: An MRI template of the Lister hooded rat brain with stereotaxic coordinates for neurosurgical implantations. Brain and neuroscience advances. 5:Article 23982128211036332. https://doi.org/10.1177/23982128211036332
Radeloff A, Nada N, El Mahallawi T, Kolkaila E, Vollmer M, Rak K, Hagen R, Schendzielorz P. 2021. Transplantation of adipose-derived stromal cells protects functional and morphological auditory nerve integrity in a model of cochlear implantation. NeuroReport. 32(9):776-782. https://doi.org/10.1097/WNR.0000000000001651
Saldeitis K, Jeschke M, Budinger E, Ohl FW, Happel MFK. 2021. Laser-Induced Apoptosis of Corticothalamic Neurons in Layer VI of Auditory Cortex Impact on Cortical Frequency Processing. Frontiers in neural circuits. 15:Article 659280. https://doi.org/10.3389/fncir.2021.659280
Schilling M, Melnik A, Ohl FW, Ritter HJ, Hammer B. 2021. Decentralized control and local information for robust and adaptive decentralized Deep Reinforcement Learning. Neural networks : the official journal of the International Neural Network Society. 144:699-725. https://doi.org/10.1016/j.neunet.2021.09.017
2020
Beitel RE, Schreiner CE, Vollmer M. 2020. Spectral plasticity in monkey primary auditory cortex limits performance generalization in a temporal discrimination task. Journal of Neurophysiology. 124(6):1798-1814. https://doi.org/10.1152/jn.00278.2020
Berdugo-Vega G, Arias-Gil G, López-Fernández A, Artegiani B, Wasielewska JM, Lee C-C, Lippert MT, Kempermann G, Takagaki K, Calegari F. 2020. Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life. Nature Communications. 11(1):Article 135. https://doi.org/10.1038/s41467-019-14026-z
Brosch M, Deckert M, Rathi S, Takagaki K, Weidner T, Ohl FW, Schmidt B, Lippert MT. 2020. An optically transparent multi-electrode array for combined electrophysiology and optophysiology at the mesoscopic scale. Journal of Neural Engineering. 17(4):Article 046014. https://doi.org/10.1088/1741-2552/aba1a4
Deane KE, Brunk MGK, Curran AW, Zempeltzi MM, Ma J, Lin X, Abela F, Aksit S, Deliano M, Ohl FW, Happel MFK. 2020. Ketamine anaesthesia induces gain enhancement via recurrent excitation in granular input layers of the auditory cortex. Journal of Physiology. 598(13):2741-2755. https://doi.org/10.1113/JP279705
Deliano M, Brunk MGK, El-Tabbal M, Zempeltzi MM, Happel MFK, Ohl FW. 2020. Dopaminergic neuromodulation of high gamma stimulus phase-locking in gerbil primary auditory cortex mediated by D1/D5-receptors. European Journal of Neuroscience. 51(5):1315-1327. https://doi.org/10.1111/ejn.13898
Dürschmid S, Reichert C, Walter N, Hinrichs H, Heinze H-J, Ohl FW, Tononi G, Deliano M. 2020. Self-regulated critical brain dynamics originate from high frequency-band activity in the MEG. PLoS ONE. 15(6):e0233589. https://doi.org/10.1371/journal.pone.0233589
Goldschmidt J, Oelschlegel A. 2020. Functional Neuroimaging in Rodents Using Cerebral Blood Flow SPECT. Frontiers in Physics. 8:Article 152. https://doi.org/10.3389/fphy.2020.00152
Heil P, Matysiak A. 2020. Absolute auditory threshold: Testing the absolute. European Journal of Neuroscience. 51(5):1224-1233. https://doi.org/10.1111/ejn.13765
Knyazeva S, Selezneva E, Gorkin A, Ohl FW, Brosch M. 2020. Representation of Auditory Task Components and of Their Relationships in Primate Auditory Cortex. Frontiers in Neuroscience. 14:Article 306. https://doi.org/10.3389/fnins.2020.00306
Kreutzmann JC, Fendt M. 2020. Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear. Translational Psychiatry. 10(1):Article 120. https://doi.org/10.1038/s41398-020-0788-8
Kreutzmann JC, Khalil R, Köhler JC, Mayer D, Florido A, Nadal R, Andero R, Fendt M. 2020. Neuropeptide-S-Receptor Deficiency Affects Sex-Specific Modulation of Safety Learning by Pre-Exposure to Electric Stimuli. Genes, Brain and Behavior. 19(3):e12621. https://doi.org/10.1111/gbb.12621
Mitlöhner J, Kaushik R, Niekisch H, Blondiaux A, Gee CE, Happel MFK, Gundelfinger E, Dityatev A, Frischknecht R, Seidenbecher C. 2020. Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses. Cells. 9(2):Article 260. https://doi.org/10.3390/cells9020260
Peterson AJ, Heil P. 2020. Phase locking of auditory-nerve fibers: the role of lowpass filtering by hair cells. Journal of Neuroscience. 40(24):4700-4714. https://doi.org/10.1523/JNEUROSCI.2269-19.2020
Rufener KS, Kauk J, Ruhnau P, Repplinger S, Heil P, Zaehle T. 2020. Inconsistent effects of stochastic resonance on human auditory processing. Scientific Reports. 10(1):Article 6419. https://doi.org/10.1038/s41598-020-63332-w
Weidner TC, Vincenz D, Brocka M, Tegtmeier J, Oelschlegel AM, Ohl FW, Goldschmidt J, Lippert MT. 2020. Matching stimulation paradigms resolve apparent differences between optogenetic and electrical VTA stimulation. Brain Stimulation. 13(2):363-371. https://doi.org/10.1016/j.brs.2019.11.005
Zempeltzi MM, Kisse M, Brunk MGK, Glemser C, Aksit S, Deane KE, Maurya S, Schneider L, Ohl FW, Deliano M, Happel MFK. 2020. Task rule and choice are reflected by layer-specific processing in rodent auditory cortical microcircuits. Communications biology. 3(1):Article 345. https://doi.org/10.1038/s42003-020-1073-3
2019
Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuña Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, Brice N, Hausrat TJ, Macharadze T, Diaz-Gonzalez S, Carlton M, Failla AV, Stork O, Schweizer M, Gundelfinger ED, Kneussel M, Spilker C, Karpova A, Kreutz MR. 2019. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nature Communications. 10(1):Article 5448. doi.org/10.1038/s41467-019-13224-z
Binder S, Mölle M, Lippert M, Bruder R, Aksamaz S, Ohl F, Wiegert JS, Marshall L. 2019. Monosynaptic hippocampal-prefrontal projections contribute to spatial memory consolidation in mice. Journal of Neuroscience. 39(35):6978-6991. https://doi.org/10.1523/JNEUROSCI.2158-18.2019
Brunk MGK, Deane KE, Kisse M, Deliano M, Vieweg S, Ohl FW, Lippert MT, Happel MFK. 2019. Optogenetic stimulation of the VTA modulates a frequency-specific gain of thalamocortical inputs in infragranular layers of the auditory cortex. Scientific Reports. 9(1):Article 20385. https://doi.org/10.1038/s41598-019-56926-6
Coors A, Brosch M, Kahl E, Khalil R, Michels B, Laub A, Franke K, Gerber B, Fendt M. 2019. Rhodiola rosea root extract has antipsychotic-like effects in rodent models of sensorimotor gating. Journal of Ethnopharmacology. 235:320-328. https://doi.org/10.1016/j.jep.2019.02.031
Heil P, Peterson AJ. 2019. Nelson's notch in the rate-level functions of auditory-nerve fibers might be caused by PIEZO2-mediated reverse-polarity currents in hair cells. Hearing Research. 381:Article 107783. https://doi.org/10.1016/j.heares.2019.107783
Huang Y, Heil P, Brosch M. 2019. Associations between sounds and actions in early auditory cortex of nonhuman primates. eLife. 8:Article e43281. https://doi.org/10.7554/eLife.43281
Macharadze T, Budinger E, Brosch M, Scheich H, Ohl FW, Henschke JU. 2019. Early Sensory Loss Alters the Dendritic Branching and Spine Density of Supragranular Pyramidal Neurons in Rodent Primary Sensory Cortices. Frontiers in neural circuits. 13:Article 61. https://doi.org/10.3389/fncir.2019.00061
Niekisch H, Steinhardt J, Berghäuser J, Bertazzoni S, Kaschinski E, Kasper J, Kisse M, Mitlöhner J, Singh JB, Weber J, Frischknecht R, Happel MFK. 2019. Learning induces transient upregulation of brevican in the auditory cortex during consolidation of long-term memories. Journal of Neuroscience. 39(36):7049-7060. https://doi.org/10.1523/JNEUROSCI.2499-18.2019
Peterson AJ, Heil P. 2019. Phase Locking of Auditory-Nerve Fibers Reveals Stereotyped Distortions and an Exponential Transfer Function with a Level-Dependent Slope. Journal of Neuroscience. 39(21):4077-4099. https://doi.org/10.1523/JNEUROSCI.1801-18.2019
Saldeitis K, Richter K, Fischer K-D, Ohl FW, Mateos JM, Budinger E. 2019. Ultrastructure of giant thalamic terminals in the auditory cortex. European Journal of Neuroscience. 50(9):3445-3453. https://doi.org/10.1111/ejn.14509
Schicknick H, Henschke JU, Budinger E, Ohl FW, Gundelfinger ED, Tischmeyer W. 2019. β-adrenergic modulation of discrimination learning and memory in the auditory cortex. European Journal of Neuroscience. 50(7):3141-3163. https://doi.org/10.1111/ejn.14480
Schilling M, Ritter H, Ohl FW. 2019. From crystallized adaptivity to fluid adaptivity in deep reinforcement learning-insights from biological systems on adaptive flexibility. In 2019 IEEE International Conference on Systems, Man and Cybernetics, SMC 2019. Institute of Electrical and Electronics Engineers Inc. pp. 1472-1478. (Conference Proceedings - IEEE International Conference on Systems, Man and Cybernetics). https://doi.org/10.1109/SMC.2019.8914302
Wendemuth A, Boeck R, Nuernberger A, Al-Hamadi A, Brechmann A, Ohl FW. 2019. Intention-Based Anticipatory Interactive Systems. In Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc. pp. 2583-2588. https://doi.org/10.1109/SMC.2018.00442
Xia Z, Arias-Gil G, Deckert M, Vollmer M, Curran A, Herrera-Molina R, Brosch M, Krug K, Schmidt B, Ohl FW, Lippert MT, Takagaki K. 2019. Electrochemical Roughening and Carbon Nanotube Coating of Tetrodes for Chronic Single-Unit Recording. bioRxiv. https://doi.org/10.1101/738245
2018
Brocka M, Helbing C, Vincenz D, Scherf T, Montag D, Goldschmidt J, Angenstein F*, Lippert M*. 2018. Contributions of dopaminergic and non-dopaminergic neurons to VTA-stimulation induced neurovascular responses in brain reward circuits. NeuroImage. 177:88-97. https://doi.org/10.1016/j.neuroimage.2018.04.059 *equal contribution
Brunk M, Sputh S, Doose S, Van De Linde S, Terpitz U. 2018. HyphaTracker: An ImageJ toolbox for time-resolved analysis of spore germination in filamentous fungi. Scientific Reports. 8(1):Article 605. doi.org/10.1038/s41598-017-19103-1
Deckert M, Lippert MT, Krzemiñski J, Takagaki K, Ohl F, Schmidt B. 2018. Polyimide Foil Flip-Chip Direct Bonding. Dziedzic A, Jasinski P, Hrsg. in EMPC 2017 - 21st European Microelectronics and Packaging Conference and Exhibition. IEEE. S. 1-4. doi.org/doi: 10.23919/EMPC.2017.8346897
Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T. 2018. JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation. Journal of Clinical Investigation. 128(10):4359-4371. https://doi.org/10.1172/JCI90312
Henschke JU, Oelschlegel AM, Angenstein F, Ohl FW, Goldschmidt J, Kanold PO, Budinger E. 2018. Early sensory experience influences the development of multisensory thalamocortical and intracortical connections of primary sensory cortices. Brain Structure and Function. 223(3):1165-1190. https://doi.org/10.1007/s00429-017-1549-1
Henschke JU, Ohl FW, Budinger E. 2018. Crossmodal connections of primary sensory cortices largely vanish during normal aging. Frontiers in Aging Neuroscience. 10(MAR). https://doi.org/10.3389/fnagi.2018.00052
Lippert MT, Takagaki K, Weidner T, Brocka M, Tegtmeier J, Ohl FW. 2018. Optogenetic Intracranial Self-Stimulation as a Method to Study the Plasticity-Inducing Effects of Dopamine. Manahan-Vaughan D, editor. In Handbook of in Vivo Neural Plasticity Techniques. Elsevier. pp. 311-326. (Handbook of Behavioral Neuroscience). https://doi.org/10.1016/B978-0-12-812028-6.00017-3
Peterson AJ, Heil P. 2018. A simple model of the inner-hair-cell ribbon synapse accounts for mammalian auditory-nerve-fiber spontaneous spike times. Hearing Research. 363:1-27. https://doi.org/10.1016/j.heares.2017.09.005
Peterson AJ, Huet A, Bourien J, Puel JL, Heil P. 2018. Recovery of auditory-nerve-fiber spike amplitude under natural excitation conditions. Hearing Research. 370:248-263. https://doi.org/10.1016/j.heares.2018.08.007
Schulz AL, Woldeit ML, Ohl FW. 2017. Neurobiological fundamentals of strategy change: A core competence of companion-systems. Biundo S, Wendemuth A, editors. In Cognitive Technologies: A Paradigm Shift in Human-Technology Interaction. Springer Verlag. pp. 145-166. (Cognitive Technologies). https://doi.org/10.1007/978-3-319-43665-4_8
Tegtmeier J, Brosch M, Janitzky K, Heinze H-J, Ohl FW*, Lippert MT*. 2018. CAVE: An Open-Source Tool for Combined Analysis of Head-Mounted Calcium Imaging and Behavior in MATLAB. Frontiers in Neuroscience. 12. https://doi.org/10.3389/fnins.2018.00958
Vollmer M. 2018. Neural processing of acoustic and electric interaural time differences in normal-hearing gerbils. Journal of Neuroscience. 38(31):6949-6966. https://doi.org/10.1523/JNEUROSCI.3328-17.2018
2017
Diepenbrock JP, Jeschke M, Ohl FW, Verhey JL. 2017. Comodulation masking release in the inferior colliculus by combined signal enhancement and masker reduction. Journal of Neurophysiology. 117(2):853-867. https://doi.org/10.1152/jn.00191.2016
Friedrich B, Heil P. 2017. Onset-duration matching of acoustic stimuli revisited: Conventional arithmetic vs. proposed geometric measures of accuracy and precision. Frontiers in Psychology. 7(JAN). https://doi.org/10.3389/fpsyg.2016.02013
Happel MFK, Ohl FW. 2017. Compensating level-dependent frequency representation in auditory cortex by synaptic integration of corticocortical input. PLoS ONE. 12(1). https://doi.org/10.1371/journal.pone.0169461
Heil P, Matysiak A, Neubauer H. 2017. A probabilistic Poisson-based model accounts for an extensive set of absolute auditory threshold measurements. Hearing Research. 353:135-161. https://doi.org/10.1016/j.heares.2017.06.011
Heil P, Peterson AJ. 2017. Spike timing in auditory-nerve fibers during spontaneous activity and phase locking. Synapse. 71(1):5-36. https://doi.org/10.1002/syn.21925
Homma NY, Happel MFK, Nodal FR, Ohl FW, King AJ, Bajo VM. 2017. A role for auditory corticothalamic feedback in the perception of complex sounds. Journal of Neuroscience. 37(25):6149-6161. https://doi.org/10.1523/JNEUROSCI.0397-17.2017
Michels B, Saumweber T, Biernacki R, Thum J, Glasgow RDV, Schleyer M, Chen YC, Eschbach C, Stocker RF, Toshima N, Tanimura T, Louis M, Arias-Gil G, Marescotti M, Benfenati F, Gerber B. 2017. Pavlovian conditioning of larval Drosophila: An illustrated, multilingual, hands-on manual for odor-taste associative learning in maggots. Frontiers in Behavioral Neuroscience. 11. https://doi.org/10.3389/fnbeh.2017.00045
Scherf T, Angenstein F. 2017. Hippocampal CA3 activation alleviates fMRI-BOLD responses in the rat prefrontal cortex induced by electrical VTA stimulation. PLoS ONE. 12(2). https://doi.org/10.1371/journal.pone.0172926
Schulz AL, Woldeit ML, Ohl FW. 2017. Neurobiological fundamentals of strategy change: A core competence of companion-systems. Biundo S, Wendemuth A, editors. In Cognitive Technologies: A Paradigm Shift in Human-Technology Interaction. Springer Verlag. pp. 145-166. (Cognitive Technologies). https://doi.org/10.1007/978-3-319-43665-4_8
Takagaki K, Ohl F. 2017. Complexity and Synergetics: Coarse-graining to investigate cerebral cortex dynamics: The case for experimental simplification of biological phenomena. Müller SC, Plath PJ, Radons G, Fuchs A, editors. In Complexity and Synergetics. 1 ed. Springer. pp. 289 - 299. https://doi.org/10.1007/978-3-319-64334-2
Töpperwien M, Krenkel M, Vincenz D, Stöber F, Oelschlegel AM, Goldschmidt J*, Salditt T*. 2017. Three-dimensional mouse brain cytoarchitecture revealed by laboratory-based x-ray phase-contrast tomography. Scientific Reports. 7. https://doi.org/10.1038/srep42847 *equal contribution
Vincenz D, Wernecke KEA, Fendt M, Goldschmidt J. 2017. Habenula and interpeduncular nucleus differentially modulate predator odor-induced innate fear behavior in rats. Behavioural Brain Research. 332:164-171. https://doi.org/10.1016/j.bbr.2017.05.053
2016
Arias-Gil G, Ohl FW, Takagaki K, Lippert MT. 2016. Measurement, modeling, and prediction of temperature rise due to optogenetic brain stimulation. Neurophotonics. 3(4). https://doi.org/10.1117/1.NPh.3.4.045007
Deckert M, Lippert M, Takagaki K, Brose A, Ohl F, Schmidt B. 2016. Fabrication of MEMS-based 3DµECoG-MEAs. Current Directions in Biomedical Engineering. 2(1):83-86. https://doi.org/10.1515/cdbme-2016-0021
Frischknecht R, Happel MFK. 2016. Einfluss der Extrazellulären Matrix auf plastische Prozesse in jungen und alten Gehirnen: Extrazelluläre Matrix und Hirnplastizität. Neuroforum. 22(1):1-9. https://doi.org/10.1007/S12269-015-0033-1
Górska U, Gociewicz K, Koculak M, Jurasińska A, Brocka M, Binder M. 2016. Zaburzenia świadomości z perspektywy neuroobrazowania. Aktualnosci Neurologiczne. 16(1):37-49. https://doi.org/10.15557/AN.2016.0006
Happel MFK. 2016. Dopaminergic impact on local and global cortical circuit processing during learning. Behavioural Brain Research. 299:32-41. https://doi.org/10.1016/j.bbr.2015.11.016
Helbing C, Brocka M, Scherf T, Lippert MT, Angenstein F. 2016. The role of the mesolimbic dopamine system in the formation of blood-oxygen-level dependent responses in the medial prefrontal/anterior cingulate cortex during high-frequency stimulation of the rat perforant pathway. Journal of Cerebral Blood Flow and Metabolism. 36(12):2177-2193. https://doi.org/10.1177/0271678X15615535
Homma NY, Bajo VM, Happel MFK, Nodal FR, King AJ. 2016. Mistuning detection performance of ferrets in a go/no-go task. Journal of the Acoustical Society of America. 139(6):EL246-EL251. https://doi.org/10.1121/1.4954378
Huang Y, Matysiak A, Heil P, König R, Brosch M. 2016. Persistent neural activity in auditory cortex is related to auditory working memory in humans and nonhuman primates. eLife. 5(JULY). https://doi.org/10.7554/eLife.15441
Jarvers C, Brosch T, Brechmann A, Woldeit ML, Schulz AL, Ohl FW, Lommerzheim M, Neumann H. 2016. Reversal learning in humans and gerbils: Dynamic control network facilitates learning. Frontiers in Neuroscience. 10(NOV). https://doi.org/10.3389/fnins.2016.00535
Kähne T, Richter S, Kolodziej A, Smalla KH, Pielot R, Engler A, Ohl FW, Dieterich DC, Seidenbecher C, Tischmeyer W, Naumann M, Gundelfinger ED. 2016. Proteome rearrangements after auditory learning: high-resolution profiling of synapse-enriched protein fractions from mouse brain. Journal of Neurochemistry. 138(1):124-138. https://doi.org/10.1111/jnc.13636
Ohl FW. 2016. On the creation of meaning in the brain-cortical neurodynamics during category learning. In Studies in Systems, Decision and Control. Springer International Publishing. pp. 147-159. (Studies in Systems, Decision and Control). https://doi.org/10.1007/978-3-319-24406-8_14
Schulz AL, Woldeit ML, Gonçalves AI, Saldeitis K, Ohl FW. 2016. Selective Increase of Auditory Cortico-Striatal Coherence during Auditory-Cued Go/NoGo Discrimination Learning. Frontiers in Behavioral Neuroscience. 9:368. https://doi.org/10.3389/fnbeh.2015.00368
Spilker C*, Nullmeier S*, Grochowska KM*, Schumacher A, Butnaru I, Macharadze T, Gomes GM, YuanXiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bär J, D’Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR. 2016. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genetics. 12(3). https://doi.org/10.1371/journal.pgen.1005907 *equal contribution
Takagaki K, Morales MK, Vitantonio D, Berkowitz F, Bell WL, Kumar PN, Motamedi GK. 2016. Periodic Lateralized Epileptiform Discharges (PLEDs) in Patients with Neurosyphilis and HIV Infection. Clinical EEG and Neuroscience. 47(3):247-250. https://doi.org/10.1177/1550059414552704
2015
Budinger E, Brechmann A, Brosch M, Heil P, König R, Ohl FW, Scheich H. 2015. Auditory cortex 2014 - towards a synthesis of human and animal research. European Journal of Neuroscience. 41(5):515-517. doi.org/10.1111/ejn.12832
Deike S, Heil P, Böckmann-Barthel M, Brechmann A. 2015. Decision making and ambiguity in auditory stream segregation. Frontiers in Neuroscience. 9(JUL). https://doi.org/10.3389/fnins.2015.00266
Happel MFK, Deliano M, Ohl FW. 2015. Combined shuttle-box training with electrophysiological cortex recording and stimulation as a tool to study perception and learning. Journal of Visualized Experiments. 2015(105). https://doi.org/10.3791/53002
Heil P, Peterson AJ. 2015. Basic response properties of auditory nerve fibers: a review. Cell and Tissue Research. 361(1):129-158. https://doi.org/10.1007/s00441-015-2177-9
Ilango A, Lobo MK. 2015. Shining light on motivation, emotion, and memory processes. Frontiers in Behavioral Neuroscience. 9(JAN):1-3. https://doi.org/10.3389/fnbeh.2015.00001
Janitzky K, Lippert MT, Engelhorn A, Tegtmeier J, Goldschmidt J, Heinze HJ, Ohl FW. 2015. Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task. Frontiers in Behavioral Neuroscience. 9(NOVEMBER). https://doi.org/10.3389/fnbeh.2015.00286
König R, Matysiak A, Kordecki W, Sieluzycki C, Zacharias N, Heil P. 2015. Averaging auditory evoked magnetoencephalographic and electroencephalographic responses: A critical discussion. European Journal of Neuroscience. 41(5):631-640. https://doi.org/10.1111/ejn.12833
Meyer AF, Diepenbrock JP, Ohl FW, Anemüller J. 2015. Fast and robust estimation of spectro-temporal receptive fields using stochastic approximations. Journal of Neuroscience Methods. 246:119-133. https://doi.org/10.1016/j.jneumeth.2015.02.009
Mylius J, Happel MFK, Gorkin AG, Huang Y, Scheich H, Brosch M. 2015. Fast transmission from the dopaminergic ventral midbrain to the sensory cortex of awake primates. Brain Structure and Function. 220(6):3273-3294. https://doi.org/10.1007/s00429-014-0855-0
Oelschlegel AM, Geissen M, Lenk M, Riebe R, Angermann M, Schaetzl H, Groschup MH. 2015. A bovine cell line that can be infected by natural sheep scrapie prions. PLoS ONE. 10(1):e0117154. https://doi.org/10.1371/journal.pone.0117154
Ohl FW. 2015. Role of cortical neurodynamics for understanding the neural basis of motivated behavior - lessons from auditory category learning. Current Opinion in Neurobiology. 31:88-94. doi.org/10.1016/j.conb.2014.08.014
Scherf T, Angenstein F. 2015. Postsynaptic and spiking activity of pyramidal cells, the principal neurons in the rat hippocampal CA1 region, does not control the resultant BOLD response: A combined electrophysiologic and fMRI approach. Journal of Cerebral Blood Flow and Metabolism. 35(4):565-575. https://doi.org/10.1038/jcbfm.2014.252
Takagaki K, Russell J, Lippert MT, Motamedi GK. 2015. Development of the posterior basic rhythm in children with autism. Clinical Neurophysiology. 126(2):297-303. https://doi.org/10.1016/j.clinph.2014.04.022
Tziridis K, Ahlf S, Jeschke M, Happel MFK, Ohl FW, Schulze H. 2015. Noise trauma induced neural plasticity throughout the auditory system of Mongolian gerbils: Differences between tinnitus developing and non-developing animals. Frontiers in Neurology. 6:22. https://doi.org/10.3389/fneur.2015.00022
Vitantonio D, Xu W, Geng X, Wolff BS, Takagaki K, Motamedi GK, Wu JY. 2015. Emergence of dominant initiation sites for interictal spikes in rat neocortex. Journal of Neurophysiology. 114(6):3315-3325. https://doi.org/10.1152/jn.00471.2014
Wanger T, Wetzel W, Scheich H, Ohl FW, Goldschmidt J. 2015. Spatial patterns of neuronal activity in rat cerebral cortex during non-rapid eye movement sleep. Brain Structure and Function. 220(6):3469-3484. https://doi.org/10.1007/s00429-014-0867-9
Wernecke KEA, Vincenz D, Storsberg S, D'Hanis W, Goldschmidt J, Fendt M. 2015. Fox urine exposure induces avoidance behavior in rats and activates the amygdalar olfactory cortex. Behavioural Brain Research. 279:76-81. https://doi.org/10.1016/j.bbr.2014.11.020
Woldeit M, Schulz AL, Brosch M,Wanger T,Ohl F. 2015. Superordinate strategy use of Mongolian gerbils during an auditory serial reversal task. in Proceedings of the 1st International Symposium on Companion-Technology (ISCT 2015) - September 23rd-25th, Ulm University, Germany.
2014
Górska U, Koculak M, Brocka M, Binder M. 2014. Zaburzenia s̈wiadomos̈ci - Perspektywa kliniczna i etyczna. Aktualnosci Neurologiczne. 14(3):190-198. https://doi.org/10.15557/AN.2014.0022
Happel MFK, Deliano M, Handschuh J, Ohl FW. 2014. Dopamine-modulated recurrent corticoefferent feedback in primary sensory cortex promotes detection of behaviorally relevant stimuli. Journal of Neuroscience. 34(4):1234-1247. https://doi.org/10.1523/JNEUROSCI.1990-13.2014
Happel MFK, Niekisch H, Castiblanco Rivera LL, Ohl FW, Deliano M, Frischknecht R. 2014. Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex. Proceedings of the National Academy of Sciences of the United States of America. 111(7):2800-2805. https://doi.org/10.1073/pnas.1310272111
Heil P. 2014. Towards a unifying basis of auditory thresholds: Binaural summation. JARO - Journal of the Association for Research in Otolaryngology. 15(2):219-234. doi.org/10.1007/s10162-013-0432-x
Kolodziej A, Lippert M, Angenstein F, Neubert J, Pethe A, Grosser OS, Amthauer H, Schroeder UH, Reymann KG, Scheich H, Ohl FW, Goldschmidt J. 2014. SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice. NeuroImage. 103:171-180. https://doi.org/10.1016/j.neuroimage.2014.09.023
Lison H, Happel MFK, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schröder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, Reymann KG, Rönicke R. 2014. Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death. Neurobiology of Disease. 63:62-73. https://doi.org/10.1016/j.nbd.2013.11.014
Meyer AF, Diepenbrock JP, Happel MFK, Ohl FW, Anemüller J. 2014. Discriminative learning of receptive fields from responses to non-gaussian stimulus ensembles. PLoS ONE. 9(4). https://doi.org/10.1371/journal.pone.0093062
Meyer AF, Diepenbrock JP, Ohl FW, Anemüller J. 2014. Temporal variability of spectro-temporal receptive fields in the anesthetized auditory cortex. Frontiers in Computational Neuroscience. 8(DEC). https://doi.org/10.3389/fncom.2014.00165
Michael Ilango A, Shumake J, Wetzel W, Ohl FW. 2014. Contribution of emotional and motivational neurocircuitry to cue-signaled active avoidance learning. Frontiers in Behavioral Neuroscience. 8(October). https://doi.org/10.3389/fnbeh.2014.00372
Peterson AJ, Irvine DRF, Heil P. 2014. A model of synaptic vesicle-pool depletion and replenishment can account for the interspike interval distributions and nonrenewal properties of spontaneous spike trains of auditory-nerve fibers. Journal of Neuroscience. 34(45):15097-15109. https://doi.org/10.1523/JNEUROSCI.0903-14.2014
Saldeitis K, Happel MFK, Ohl FW, Scheich H, Budinger E. 2014. Anatomy of the auditory thalamocortical system in the mongolian gerbil: Nuclear origins and cortical field-, layer-, and frequency-specificities. Journal of Comparative Neurology. 522(10):2397-2430. https://doi.org/10.1002/cne.23540
2013
Heil P, Neubauer H, Tetschke M, Irvine DRF. 2013. A probabilistic model of absolute auditory thresholds and its possible physiological basis. In Advances in Experimental Medicine and Biology. pp. 21-29. (Advances in experimental medicine and biology). https://doi.org/10.1007/978-1-4614-1590-9_3
Heil P, Verhey JL, Zoefel B. 2013. Modelling detection thresholds for sounds repeated at different delays. Hearing Research. 296:83-95. https://doi.org/10.1016/j.heares.2012.12.002
Ilango A, Shumake J, Wetzel W, Scheich H, Ohl FW. 2013. Electrical Stimulation of Lateral Habenula during Learning: Frequency-Dependent Effects on Acquisition but Not Retrieval of a Two-Way Active Avoidance Response. PLoS ONE. 8(6). https://doi.org/10.1371/journal.pone.0065684
Keating P, Nodal FR, Gananandan K, Schulz AL, King AJ. 2013. Behavioral sensitivity to broadband binaural localization cues in the ferret. JARO - Journal of the Association for Research in Otolaryngology. 14(4):561-572. https://doi.org/10.1007/s10162-013-0390-3
Lippert MT, Takagaki K, Kayser C, Ohl FW. 2013. Asymmetric Multisensory Interactions of Visual and Somatosensory Responses in a Region of the Rat Parietal Cortex. PLoS ONE. 8(5):e63631. https://doi.org/10.1371/journal.pone.0063631
Matysiak A, Kordecki W, Sieluzycki C, Zacharias N, Heil P, König R. 2013. Variance stabilization for computing and comparing grand mean waveforms in MEG and EEG. Psychophysiology. 50(7):627-639. https://doi.org/10.1111/psyp.12047
Meyer AF, Diepenbrock JP, Ohl FW, Anemuller J. 2013. Quantifying neural coding noise in linear threshold models. In International IEEE/EMBS Conference on Neural Engineering. pp. 1127-1130. https://doi.org/10.1109/NER.2013.6696136
Pohl NU, Slabbekoorn H, Neubauer H, Heil P, Klump GM, Langemann U. 2013. Why longer song elements are easier to detect: Threshold level-duration functions in the Great Tit and comparison with human data. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 199(3):239-252. https://doi.org/10.1007/s00359-012-0789-z
Traue HC, Ohl F, Schwenker F, Kessler H, Limbrecht K, Hoffmann H, Scherer S, Kotzyba M, Scheck A, Walter S. 2013. A Framework for Emotions and Dispositions in Man-Companion Interaction. In Coverbal Synchrony in Human-Machine Interaction. CRC Press. pp. 99-140.
Tyll S, Bonath B, Schoenfeld MA, Heinze HJ, Ohl FW, Noesselt T. 2013. Neural basis of multisensory looming signals. NeuroImage. 65:13-22. https://doi.org/10.1016/j.neuroimage.2012.09.056
Wanger T, Takagaki K, Lippert MT, Goldschmidt J, Ohl FW. 2013. Wave propagation of cortical population activity under urethane anesthesia is state dependent. Neuroscience. 14. https://doi.org/10.1186/1471-2202-14-78
Zoefel B, Heil P. 2013. Detection of near-threshold sounds is independent of eeg phase in common frequency bands. Frontiers in Psychology. 4(MAY). https://doi.org/10.3389/fpsyg.2013.00262
2012
Anemüller J, Caputo B, Hermansky H, Ohl FW, Pajdla T, Pavel M, Van Gool L, Vogels R, Wabnik S, Weinshall D. 2012. DIRAC: Detection and identification of rare audio-visual events. In Detection and Identification of Rare Audiovisual Cues. Springer Nature. pp. 3-35. (Studies in Computational Intelligence). Available from: 10.1007/978-3-642-24034-8_1
Apostolova I, Wunder A, Dirnagl U, Michel R, Stemmer N, Lukas M, Derlin T, Gregor-Mamoudou B, Goldschmidt J, Brenner W, Buchert R. 2012. Brain perfusion SPECT in the mouse: Normal pattern according to gender and age. NeuroImage. 63(4):1807-1817. Available from: 10.1016/j.neuroimage.2012.08.038
Budinger E, Heil P. 2012. Anatomy of the auditory cortex. In Listening to Speech: An Auditory Perspective. Taylor and Francis. pp. 91-113. Available from: 10.4324/9780203933107
Deike S, Heil P, Böckmann-Barthel M, Brechmann A. 2012. The build-up of auditory stream segregation: A different perspective. Frontiers in Psychology. 3(OCT). Available from: 10.3389/fpsyg.2012.00461
Fillbrandt A, Ohl FW. 2012. Modulations of single-trial interactions between the auditory and the visual cortex during prolonged exposure to audiovisual stimuli with fixed stimulus onset asynchrony. In Detection and Identification of Rare Audiovisual Cues. Springer Nature. pp. 155-180. (Studies in Computational Intelligence). Available from: 10.1007/978-3-642-24034-8_13
Gao X, Xu W, Wang Z, Takagaki K, Li B, Wu JY. 2012. Interactions between two propagating waves in rat visual cortex. Neuroscience. 216:57-69. Available from: 10.1016/j.neuroscience.2012.04.062
Haroon F, Händel U, Angenstein F, Goldschmidt J, Kreutzmann P, Lison H, Fischer KD, Scheich H, Wetzel W, Schlüter D, Budinger E. 2012. Toxoplasma gondii actively inhibits neuronal function in chronically infected mice. PLoS ONE. 7(4). Available from: 10.1371/journal.pone.0035516
Ilango A, Shumake J, Wetzel W, Scheich H,Ohl FW. 2012. The role of dopamine in the context of aversive stimuli with particular reference to acoustically signaled avoidance learning. Frontiers in Neuroscience. (SEP). Available from: 10.3389/fnins.2012.00132
Kähne T, Kolodziej A, Smalla KH, Eisenschmidt E, Haus UU, Weismantel R, Kropf S, Wetzel W, Ohl FW, Tischmeyer W, Naumann M, Gundelfinger ED. 2012. Synaptic proteome changes in mouse brain regions upon auditory discrimination learning. Proteomics. 12(15-16):2433-2444. Available from: 10.1002/pmic.201100669
Lovell J, Brosch M, Budinger E, Goldschmidt J, Scheich H, Tschorn S, Wendt B, Zuschratter W. 2012. Scanning and Transmission Electron Microscope Examination of Cochlea Hair and Pillar Cells from the Ear of the Mongolian Gerbil (Meriones unguiculatus). Anatomy and Physiology. 2(3).
Macharadze T, Pielot R, Wanger T, Scheich H, Gundelfinger ED, Budinger E, Goldschmidt J, Kreutz MR. 2012. Altered neuronal activity patterns in the visual cortex of the adult rat after partial optic nerve crush-a single-cell resolution metabolic mapping study. Cerebral Cortex. 22(8):1824-1833. Available from: 10.1093/cercor/bhr256
Schreiber S, Bueche CZ, Garz C, Kropf S, Angenstein F, Goldschmidt J, Neumann J, Heinze HJ, Goertler M, Reymann KG, Braun H. 2012. The pathologic cascade of cerebrovascular lesions in SHRSP: Is erythrocyte accumulation an early phase. Journal of Cerebral Blood Flow and Metabolism. 32(2):278-290. Available from: 10.1038/jcbfm.2011.122
Wanger T, Scheich H, Ohl FW, Goldschmidt J. 2012. The use of thallium diethyldithiocarbamate for mapping CNS potassium metabolism and neuronal activity: Tl +-redistribution, Tl +-kinetics and Tl +-equilibrium distribution. Journal of Neurochemistry. 122(1):106-114. Available from: 10.1111/j.1471-4159.2012.07757.x
Weinshall D, Zweig A, Hermansky H, Kombrink S, Ohl FW, Anemüller J, Bach JH, Van Gool L, Nater F, Pajdla T, Havlena M, Pavel M. 2012. Beyond novelty detection: Incongruent events, when general and specific classifiers disagree. IEEE Transactions on Pattern Analysis and Machine Intelligence. 34(10):1886-1901. Available from: 10.1109/TPAMI.2011.279
Woldeit ML, Schulz AL, Ohl FW. 2012. Phase de-synchronization effects auditory gating in the ventral striatum but not auditory cortex. Neuroscience. 216:70-81. Available from: 10.1016/j.neuroscience.2012.04.058
Zacharias N, König R, Heil P. 2012. Stimulation-history effects on the M100 revealed by its differential dependence on the stimulus onset interval. Psychophysiology. 49(7):909-919. Available from: 10.1111/j.1469-8986.2012.01370.x
2011
Brechmann A, Brosch M, Budinger E, Heil P, König R, Ohl F, Scheich H. 2011. Auditory cortex - Current concepts in human and animal research. Hearing Research. 271(1-2):1-2. Available from: 10.1016/j.heares.2010.10.016
Coomber B, Edwards D, Jones SJ, Shackleton TM, Goldschmidt J, Wallace MN, Palmer AR. 2011. Cortical inactivation by cooling in small animals. Frontiers in Systems Neuroscience. 5(JUNE 2011):53. Available from: 10.3389/fnsys.2011.00053
Heidt T, Deininger F, Peter K, Goldschmidt J, Pethe A, Hagemeyer CE, Neudorfer I, Zirlik A, Weber WA, Bode C, Meyer PT, Behe M, von zur Mühlen C. 2011. Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody. PLoS ONE. 6(3). Available from: 10.1371/journal.pone.0018446
Heil P, Neubauer H, Irvine DRF. 2011. An improved model for the rate-level functions of auditory-nerve fibers. Journal of Neuroscience. 31(43):15424-15437. Available from: 10.1523/JNEUROSCI.1638-11.2011
Ilango A, Shumake J, Wetzel W, Scheich H,Ohl FW. 2011. Effects of ventral tegmental area stimulation on the acquisition and long-term retention of active avoidance learning. Behavioural Brain Research. 225(2):515-521. Available from: 10.1016/j.bbr.2011.08.014
Scheich H, Brechmann A, Brosch M, Budinger E, Ohl FW, Selezneva E, Stark H, Tischmeyer W, Wetzel W. 2011. Behavioral semantics of learning and crossmodal processing in auditory cortex: The semantic processor concept. Hearing Research. 271(1-2):3-15. Available from: 10.1016/j.heares.2010.10.006
Scheich H, Ohl F. 2011. Direkter Zugang zum Gehirn. Spektrum der Wissenschaft.
Scheich H,Ohl FW. 2011. A semantic concept of auditory cortex function and learning. In The Auditory Cortex. Springer. pp. 369-387. Available from: 10.1007/978-1-4419-0074-6_17
Takagaki K, Perito ER, Jose FA, Heyman MB. 2011. Gastric mucosal damage from ingestion of 3 button cell batteries. Journal of Pediatric Gastroenterology and Nutrition. 53(2):222-223. Available from: 10.1097/MPG.0b013e3182107ba1
Takagaki K, Zhang C, Wu JY, Ohl FW. 2011. Flow detection of propagating waves with temporospatial correlation of activity. Journal of Neuroscience Methods. 200(2):207-218. Available from: 10.1016/j.jneumeth.2011.05.023
Tyll S, Budinger E, Noesselt T. 2011. Thalamic influences on multisensory integration. Communicative and Integrative Biology. 4(4):378-381.
Zacharias N, Sieluzycki C, Kordecki W, König R, Heil P. 2011. The M100 component of evoked magnetic fields differs by scaling factors: Implications for signal averaging. Psychophysiology. 48(8):1069-1082. Available from: 10.1111/j.1469-8986.2011.01183.x
2010
Goldschmidt J, Wanger T, Engelhorn A, Friedrich H, Happel M, Ilango A, Engelmann M, Stuermer IW, Ohl FW, Scheich H. 2010. High-resolution mapping of neuronal activity using the lipophilic thallium chelate complex TlDDC: Protocol and validation of the method. NeuroImage. 49(1):303-315. Available from: 10.1016/j.neuroimage.2009.08.012
Hammer R, Brechmann A, Ohl F, Weinshall D, Hochstein S. 2010. Differential category learning processes: The neural basis of comparison-based learning and induction. NeuroImage. 52(2):699-709. Available from: 10.1016/j.neuroimage.2010.03.080
Happel MFK, Jeschke M,Ohl FW. 2010. Spectral integration in primary auditory cortex attributable to temporally precise convergence of thalamocortical and intracortical input. Journal of Neuroscience. 30(33):11114-11127. Available from: 10.1523/JNEUROSCI.0689-10.2010
Heil P, Neubauer H, Irvine DRF. 2010. A new model for the shapes of rate-level functions of auditory-nerve fibers. In Proceedings of the 20th International Congress on Acoustics. pp. 3156-3163.
Heil P, Neubauer H. 2010. Summing across different active zones can explain the quasi-linear Ca 2+-dependencies of exocytosis by receptor cells. Frontiers in Synaptic Neuroscience. 2 Article 148(NOV):1-15. Available from: 10.3389/fnsyn.2010.00148
Ilango A, Wetzel W, Scheich H,Ohl FW. 2010. The combination of appetitive and aversive reinforcers and the nature of their interaction during auditory learning. Neuroscience. 166(3):752-762. Available from: 10.1016/j.neuroscience.2010.01.010
Lippert MT, Steudel T, Ohl FW, Logothetis NK, Kayser C. 2010. Coupling of neural activity and fMRI-BOLD in the motion area MT. Magnetic Resonance Imaging. 28(8):1087-1094. Available from: 10.1016/j.mri.2009.12.028
Moeller CK, Kurt S, Happel MFK, Schulze H. 2010. Long-range effects of GABAergic inhibition in gerbil primary auditory cortex. European Journal of Neuroscience. 31(1):49-59. Available from: 10.1111/j.1460-9568.2009.07039.x
Noesselt T, Tyll S, Boehler CN, Budinger E, Heinze HJ, Driver J. 2010. Sound-induced enhancement of low-intensity vision: Multisensory influences on human sensory-specific cortices and thalamic bodies relate to perceptual enhancement of visual detection sensitivity. Journal of Neuroscience. 30(41):13609-13623. Available from: 10.1523/JNEUROSCI.4524-09.2010
Shumake J, Ilango A, Scheich H, Wetzel W, Ohl FW. 2010. Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental area. Journal of Neuroscience. 30(17):5876-5883. Available from: 10.1523/JNEUROSCI.3604-09.2010
Woldeit ML, Korz V. 2010. Theta oscillations during holeboard training in rats: different learning strategies entail different context-dependent modulations in the hippocampus. Neuroscience. 165(3):642-653. Available from: 10.1016/j.neuroscience.2009.11.002
Zacharias N, Sieluzycki C, Matysiak MA, König R, Heil P. 2010. Relevant observations for averaging stimulus evoked magnetic fields across trials and across subjects. In 17th International Conference on Biomagnetism Advances in Biomagnetism. pp. 179-182. Available from: 10.1007/978-3-642-12197-5_39
Zaehle T, Lenz D, Ohl FW, Herrmann CS. 2010. Resonance phenomena in the human auditory cortex: Individual resonance frequencies of the cerebral cortex determine electrophysiological responses. Experimental Brain Research. 203(3):629-635. Available from: 10.1007/s00221-010-2265-8